Factor V Leiden, factor V Cambridge, factor II GA20210, and methylenetetrahydrofolate reductase in cerebral venous and sinus thrombosis: A case-control study
نویسندگان
چکیده
منابع مشابه
factor v leiden, factor v cambridge, factor ii ga20210 and mtfhr in cerebral venous and sinus thrombosis: a case-control study
background: factor v g1691a (fv leiden), fii ga20210, and methylenetetrahydrofolate reductase (mthfr) c677t mutations are the most common genetic risk factors for thromboembolism in the western countries. however, there is rare data in iran about cerebral venous and sinus thrombosis (cvst) patients. the aim of this study was to evaluate the frequency of common genetic thrombophilic factors in c...
متن کاملFactor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis
Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...
متن کاملFactor V Leiden mutation is a risk factor for cerebral venous thrombosis: a case-control study of 55 patients.
BACKGROUND AND PURPOSE Different coagulation disorders have been associated with cerebral venous thrombosis (CVT). Until now, fewer than 50 patients have been reported with CVT and the factor V Leiden (FVL) mutation. Although the prevalence of FVL-positive patients with CVT ranged from 10% to 25%, it was as low as 0.5% to 3% in the control groups. Most other studies had not systematically searc...
متن کاملHELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST)...
متن کاملcase control study of the factor v leiden and factor ii g20210a mutation frequency in women with recurrent pregnancy loss
background: recurrent pregnancy loss (rpl) caused by various genetic and non-genetic factors. after chromosome abnormality, thrombophilia is one of the most important genetic factors that could cause rpl. factor v leiden and factor ii g20210a mutation were the most common mutations cause thrombophilia in the world. objective: the purpose of this study was to determine the frequency of factor v ...
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ژورنال
عنوان ژورنال: Journal of Research in Medical Sciences
سال: 2015
ISSN: 1735-1995
DOI: 10.4103/1735-1995.165956